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Research Use Only (RUO). Not for human or veterinary use. No medical or therapeutic claims.

VIP 10mg – Premium Research Peptide

VIP (Vasoactive Intestinal Peptide) is a naturally occurring 28-amino-acid neuropeptide studied in laboratory research for its interaction with VPAC receptors and its involvement in cellular signalling pathways across a range of biological systems.

Scientific interest in VIP focuses on how peptide-mediated signalling may influence cellular communication, smooth muscle regulation, vascular signalling, immune-related pathways, and neuroendocrine processes within controlled experimental models.

Product Information

Overview

VIP is commonly investigated in experimental models involving neuropeptide signalling, receptor-mediated cellular communication, vascular biology, smooth muscle signalling, and neuroendocrine regulation. The peptide interacts primarily with VPAC1 and VPAC2 receptors, which belong to the G protein-coupled receptor family.

Laboratory investigations examine VIP signalling across multiple tissue and cellular models because VPAC receptors are distributed throughout a variety of biological systems. Research may explore receptor activation, intracellular signalling cascades, cyclic adenosine monophosphate (cAMP) pathways, and associated cellular responses.

VIP is also studied within models involving neural communication, vascular signalling, gastrointestinal biology, pulmonary tissue signalling, and immune-cell regulation. These investigations contribute to a broader understanding of how naturally occurring neuropeptides participate in communication between different cellular systems.

Potential Research Applications

• VPAC1 and VPAC2 receptor signalling research
• Neuropeptide signalling pathway investigations
• Vascular and smooth muscle signalling studies
• Neuroendocrine communication research
• Cellular cAMP signalling investigations
• Gastrointestinal signalling research models
• Pulmonary and respiratory tissue signalling studies
• Immune-cell and inflammatory signalling research

Scientific Background

Vasoactive Intestinal Peptide is a 28-amino-acid peptide belonging to the secretin/glucagon peptide family. Although originally identified in gastrointestinal tissue research, VIP has subsequently been observed across numerous biological systems, including neural, endocrine, cardiovascular, respiratory, and immune-related tissues.

VIP primarily interacts with the VPAC1 and VPAC2 receptors. These receptors are G protein-coupled receptors that can activate intracellular signalling pathways involving adenylate cyclase and cAMP. Laboratory models use these receptor interactions to investigate how extracellular peptide signals are translated into downstream cellular responses.

The distribution of VIP and its receptors across different tissues has made the peptide an important research tool for examining communication between neural, vascular, endocrine, gastrointestinal, and immune systems. Experimental investigations may evaluate receptor expression, intracellular signalling, cellular responsiveness, and tissue-specific differences in VIP-mediated pathways.

Research also examines the relationship between VIP signalling and smooth muscle activity, vascular tone mechanisms, neuroendocrine communication, epithelial signalling, and immune-cell responses. These experimental models provide insight into the broader biological functions of peptide-mediated receptor signalling.

Ongoing scientific research continues to explore VIP as a tool for understanding VPAC receptor biology, neuropeptide communication, intracellular signalling pathways, and tissue-specific cellular responses within controlled laboratory environments.

Safety and Handling

This compound is supplied strictly for laboratory research purposes. Handling should be performed by qualified personnel using appropriate laboratory safety procedures, suitable protective equipment, and controlled research conditions.

The product should be stored securely under appropriate laboratory conditions and protected from excessive heat, moisture, and direct light. Appropriate procedures should be followed when handling, storing, and preparing the compound for experimental research.

Use outside intended research applications is not recommended.

Disclaimer

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