Adonis MOTS-C – Research Peptide – (RUO)

Research Use Only (RUO). Not for human or veterinary use. No medical or therapeutic claims.

MOTS-c Peptide – Research Grade (Mitochondrial-Derived Peptide)

Buy MOTS-c peptide for research — MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA type-c) is a mitochondrial-derived peptide known for its unique role in metabolic regulation, AMPK activation, and energy homeostasis. Researchers are studying this peptide for its potential impact on mitochondrial communication, glucose metabolism, and endurance performance.

For detailed analysis and scientific context, visit our MOTS-c Research Blog.

Product Information

Overview

MOTS-c peptide is a 16-amino-acid mitochondrial peptide that influences metabolic adaptation, cellular stress response, and energy regulation. It acts primarily by stimulating the AMPK pathway — the key regulator of energy balance in cells. Researchers are exploring its role in improving glucose tolerance, promoting lipid oxidation, and enhancing mitochondrial efficiency.

Potential Research Applications

• AMPK activation and metabolic regulation studies
• Mitochondrial biogenesis and energy metabolism research
• Exercise performance and endurance physiology models
• Cellular stress and longevity studies
• Insulin sensitivity and metabolic syndrome research

Scientific Background

Discovered in 2015, MOTS-c was the first peptide identified to be encoded in mitochondrial DNA and translated within the cytoplasm. It represents a new class of bioactive peptides known as mitochondrial-derived peptides (MDPs).
Research suggests that MOTS-c acts as a key messenger linking mitochondrial function to cellular metabolism — influencing gene expression, promoting mitochondrial biogenesis, and improving stress resistance in laboratory studies.

Safety and Handling

MOTS-c is supplied strictly for scientific and research purposes. It is not approved for human or veterinary use. Appropriate laboratory safety protocols must be observed when handling and reconstituting MOTS-c powder. Avoid repeated freeze–thaw cycles and ensure sterile conditions at all times.

Disclaimer

This peptide is intended solely for laboratory research. It is not approved for medical, therapeutic, or human consumption purposes. Buyers must ensure compliance with applicable regulations regarding the use of research compounds.

Explore related compounds in our Research Peptide Shop or read more in our Peptide Research Blog.